PERFUSION REPORTS

REPORT
039
DATE
1/10/2018
TITLE
Pall Clot In Cardioplegia Circuit
DETAILS OF INCIDENT

The case described was a MVR+CABG. The circuit used had been primed for a possible case which was then cancelled the day prior. The cardioplegia (CP) circuit had a leukoguard BC2 filter placed between the oxygenator and the cardioplegia pump. A microplegia system was used. Following aortic cross clamp, 7 litres of cardioplegia were given in both ante and retro directions, approx. every 15 minutes.

Following a 15-minute period a further dose of CP was requested but as the cardioplegia pump was turned on the CP line pressure immediately rose over 300mmHg and the pump stopped and alarmed. The line was checked to the table for clamps or occlusions. The surgeon checked the system and stated that everything was unclamped at the table. The CP delivery line was then disconnected from the CP cannula and placed over a bowl whilst we tried to pump CP again. However, the pressure in the system immediately shot up to 300mmHg with no flow into the bowl. Flow could be achieved through the CP circuit recirculation line, so the table line was under suspicion.

A new table line was handed up to the table. As the original CP table line was disconnected a long clot slid out of the tubing and onto the floor. The ACT at this point was 462 (sample taken 10 mins earlier) and this was the lowest it had been. An extra 5000iu was given as a precaution. The main circuit was thoroughly checked for clots, but none were evident, and the surgeon stated no clots were visible anywhere in the chest. I discarded the whole CP circuit and set up a new one. By this time the surgeon was ready to remove the cross clamp, so no more CP was required.

On later inspection of the old CP circuit, clot was evident all around the bubble trap section of the heat exchanger. In addition, the BC2 filter seemed clogged post filter membrane. There was no apparent harm to the patient from this incident in terms of coming off CPB and the patient’s post-op course was as expected.

DETAILS OF INJURY TO PATIENT

None

TYPE OF DEVICE/MANUFACTURER

N/A

ACTION TAKEN

Thoughts Of Reporting Perfusion Scientist:

“With hindsight I should not have run 7 litres of CP through the BC2 (the manufacturers recommend a limit of 3 litres). Why the clots formed I don’t know. There may well be some connection to the clogged BC2 filter, as it became more and more clogged there would be an increasing negative pressure between filter and pump. Evidence of this was seen by the syringe driver alarming a ‘drive fault’ as it tried to pump into a negative pressure. There was also a theory about HIT and cold agglutination but tests for both have reported negative. There was no suggestion that there was any fault with the CP device.”

Learning Outcomes

An internal incident reporting process was completed. The use of BC2 filters for cardioplegia is to be strictly limited to 3litres as per the manufacturers instructions for use.

RESPONSE FROM MANUFACTURER

The pump was thoroughly checked by the servicing engineer, and no fault was identified.

ADDTIONAL INFORMATION
SUPPORTING VISUALS/VIDEO

N/A

SUPPORTING DOCUMENT

OTHER PERFUSION
 REPORTS

London Core Review Cardiothoracic Surgery Course - Touch icon
London Core Review Cardiothoracic Surgery Course - Help Guide
Select and scroll to view chosen report
REPORT NO
123
5/7/24
Hardware Fault
REPORT NO
122
5/4/24
Oxygenator Failure
REPORT NO
121
8/3/24
Disposables: Eurosets Adult ECMO Oxygenator
REPORT NO
120
1/5/24
Disposable Incident
REPORT NO
119
Hardware: HCU Contamination
REPORT NO
118
12/9/23
Human Factors: ECMO Mobilisation
REPORT NO
117
27/9/23
Disposables: Oxygenator
REPORT NO
116
14/9/23
Disposable Issue: Reservoir in CPB circuit
REPORT NO
115
13/9/23
Disposable Error
REPORT NO
114
13/7/23
Dispoables
REPORT NO
112
20/2/23
HLM Hardware Error: S5 HLM - Dual roller cardioplegia
REPORT NO
111
10/2/23
Human Factors
REPORT NO
110
31/1/23
DISPOSABLE FAULT
REPORT NO
109
19/1/23
Disposable issue
REPORT NO
108
3/1/23
Disposable issue: Oxygenator leak
REPORT NO
107
6/12/22
Hardware fault. Electronic gas Blender failure
REPORT NO
106
1/11/22
ECG Interference
REPORT NO
105
9/9/22
Issue with use of disposable
REPORT NO
104
13/6/22
Human Factors
REPORT NO
103
25/7/22
Human Factors
REPORT NO
102
7/7/22
Disposable issue
REPORT NO
101
6/4/21
Irregular blood flow/foreign looking substance in Oxygenator
REPORT NO
100
20/4/22
Gas Line Filter Fault
REPORT NO
099
20/4/22
Human Factors: BiVAD Error
REPORT NO
098
4/4/22
REPORT NO
097
19/3/22
Disposables Issue
REPORT NO
096
18/3/22
Bubbles Sensor Activation
REPORT NO
095
1/1/22
Protamine Administration
REPORT NO
094
1/11/21
Oxygenation failure upon commencement of CPB
REPORT NO
093
1/11/21
Detached bullet tip of sump-updated response Sep 2022
Perfusion Report cards are shown in batches of 30 at any one time where available.
123
122
121
120
119
118
117
116
115
114
112
111
110
109
108
107
106
105
104
103
102
101
100
099
098
097
096
095
094
093
092
091
090
089
088
087
086
085
084
083
082
081
080
079
078
077
076
075
074
073
072
071
070
069
068
067
066
065
064
063
062
061
060
059
058
057
056
055
054
053
052
051
050
049
048
047
046
045
044
043
042
041
040
039
038
037
036
035
034
033
032
031
030
029
028
027
026
025
024
023
London Core Review Cardiothoracic Surgery Course - Touch icon
London Core Review Cardiothoracic Surgery Course - Help Guide
Know the report number? Scroll horizontally through the circle icons and select to view the appropriate report.