PERFUSION REPORTS

REPORT
039
DATE
1/10/2018
TITLE
Pall Clot In Cardioplegia Circuit
DETAILS OF INCIDENT

The case described was a MVR+CABG. The circuit used had been primed for a possible case which was then cancelled the day prior. The cardioplegia (CP) circuit had a leukoguard BC2 filter placed between the oxygenator and the cardioplegia pump. A microplegia system was used. Following aortic cross clamp, 7 litres of cardioplegia were given in both ante and retro directions, approx. every 15 minutes.

Following a 15-minute period a further dose of CP was requested but as the cardioplegia pump was turned on the CP line pressure immediately rose over 300mmHg and the pump stopped and alarmed. The line was checked to the table for clamps or occlusions. The surgeon checked the system and stated that everything was unclamped at the table. The CP delivery line was then disconnected from the CP cannula and placed over a bowl whilst we tried to pump CP again. However, the pressure in the system immediately shot up to 300mmHg with no flow into the bowl. Flow could be achieved through the CP circuit recirculation line, so the table line was under suspicion.

A new table line was handed up to the table. As the original CP table line was disconnected a long clot slid out of the tubing and onto the floor. The ACT at this point was 462 (sample taken 10 mins earlier) and this was the lowest it had been. An extra 5000iu was given as a precaution. The main circuit was thoroughly checked for clots, but none were evident, and the surgeon stated no clots were visible anywhere in the chest. I discarded the whole CP circuit and set up a new one. By this time the surgeon was ready to remove the cross clamp, so no more CP was required.

On later inspection of the old CP circuit, clot was evident all around the bubble trap section of the heat exchanger. In addition, the BC2 filter seemed clogged post filter membrane. There was no apparent harm to the patient from this incident in terms of coming off CPB and the patient’s post-op course was as expected.

DETAILS OF INJURY TO PATIENT

None

TYPE OF DEVICE/MANUFACTURER

N/A

ACTION TAKEN

Thoughts Of Reporting Perfusion Scientist:

“With hindsight I should not have run 7 litres of CP through the BC2 (the manufacturers recommend a limit of 3 litres). Why the clots formed I don’t know. There may well be some connection to the clogged BC2 filter, as it became more and more clogged there would be an increasing negative pressure between filter and pump. Evidence of this was seen by the syringe driver alarming a ‘drive fault’ as it tried to pump into a negative pressure. There was also a theory about HIT and cold agglutination but tests for both have reported negative. There was no suggestion that there was any fault with the CP device.”

Learning Outcomes

An internal incident reporting process was completed. The use of BC2 filters for cardioplegia is to be strictly limited to 3litres as per the manufacturers instructions for use.

RESPONSE FROM MANUFACTURER

The pump was thoroughly checked by the servicing engineer, and no fault was identified.

ADDTIONAL INFORMATION
SUPPORTING VISUALS/VIDEO

N/A

SUPPORTING DOCUMENT

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